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主营:激动剂、拮抗剂、抑制剂
℡ 4000-520-616
℡ 4000-520-616
Hello Bio/L-Quisqualic acid/HB0387/5mg
产品编号:HB0387-5mg
市  场 价:¥1833.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$94.00
品      牌: Hello Bio
公      司:Hello Bio
公司分类:
Hello Bio/L-Quisqualic acid/HB0387/5mg
商品介绍

Product overview

  • Name
    L-Quisqualic acid
  • Short description
    AMPA receptor agonist / group I mGlu agonist
  • Biological description

    AMPA receptor agonist / group I mGlu agonist.

    Sensitizes neurons to excitatory amino acid analogues such as L-AP4, L-AP6 and L-AbetaH ("the Quis effect").

    Can act as an excitotoxin and is used to lesion areas of the brain in rat models.

  • Biological action
    Agonist
  • Purity
    >99%
  • Our products in action
    Submit Your Citation Now

Properties

  • Chemical name
    (L)-(+)-α-Amino-3,5-dioxo-1,2,4-oxadiazolidine-2-propanoic acid
  • Molecular Weight
    189.13
  • Chemical structure
    L-Quisqualic acid  [52809-07-1]
  • Molecular Formula
    C5H7N3O5
  • CAS Number
    52809-07-1

Storing and Using Your Product

  • Storage instructions
    room temperature
  • Solubility overview
    soluble in NaOH(aq) (100mM, 1eq. NaOH) or water (10mM)
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for L-Quisqualic acid

  • L-Quisqualic acid transport into hippocampal neurons by a cystine-sensitive carrier is required for the induction of quisqualate sensitization.

    Chase LA et al (2001) Neuroscience 106(2) : 287-301.
    PubMedID: 11566501
  • C-fos expression in the rat nucleus basalis upon excitotoxic lesion with quisqualic acid: a study in adult and aged animals.

    Giovannelli L et al (1998) J Neural Transm 105(8-9) : 935-48.
    PubMedID: 9869327
  • Prolonged nociceptive responses to hind paw formalin injection in rats with a spinal cord injury.

    Lee JW et al (2008) Neurosci Lett 439(2) : 212-5.
    PubMedID: 18524486
  • Effects of quisqualic acid analogs on metabotropic glutamate receptors coupled to phosphoinositide hydrolysis in rat hippocampus.

    Littman L et al (1995) Neuropharmacology 34(8) : 829-41.
    PubMedID: 8532164
品牌介绍

Hello Bio由一群经验丰富的科学家和化学家组成,他们真心希望支持生命科学研究。Hello Bio的目标是生产和供应一系列高质量的生命科学工具,价格如此之低,使尽可能多的研究人员能够买得起。Hello Bio公司的目标是制造和供应一系列高质量的生命科学试剂,产品包括一系列激动剂,拮抗剂,抑制剂,激活剂,抗体和荧光工具,我们公司产品的价格是其他公司产品价格的一半,以便尽可能多的研究人员能够用得起。

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