Hello Bio/Anisomycin/HB2239/100mg,Hello Bio,,Hello Bio,hellobio,+,,Array.Array.Array蚂蚁淘厂家直采.

产品名称：Hello Bio/Anisomycin/HB2239/100mg

产品编号：HB2239

市场价：¥6435.00

场地：美国(厂家直采)

产品分类：生化试剂>缓冲液>酸碱缓冲液>

联系QQ：1570468124

电话号码：4000-520-616

邮箱： info@ebiomall.com

美元价：$330.00

品牌： Hello Bio

公司：Hello Bio

公司分类：

商品介绍

Productoverview

Name
Anisomycin
Shortdescription
Proteinsynthesisinhibitor.PotentJNK/p38MAPKactivator.
BIOLOGicaldescription
ProteinsynthesisinhibitorwhichpreventselongationandcausespolysomestABIlizationbybindingtothe60Sribosomalsubunittopreventpeptidebondformation.
AlsoactsasapotentJNKandp38MAPKactivator.

Initiatesintracellularsignalsforrapidinductionofimmediate-early(IE)genes(e.g.c-fos,fosB,c-jun,JunBandJunD).

Additionally,thoughttoblocklatelong-termpotentiation(L-LTP)andathighdosesreducesneuronalactivity.
Alternativenames
ANI|Flagecidin
Biologicalaction
Antibiotic
Ourproductsinaction
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Properties

Chemicalname
(2R,3S,4S)-2-[(4-Methoxyphenyl)methyl]-3,4-pyrrolidinediol3-acetate
MolecularWeight
265.31
MolecularFormula
C₁₄H₁₉NO₄
CASNumber
22862-76-6
PubChemidentifier
253602
SMILES
CC(=O)O[C@@H]1[C@H](CN[C@@H]1CC2=CC=C(C=C2)OC)O
InChiKey
YKJYKKNCCRKFSL-RDBSUJKOSA-N
MDLnumber
MFCD00077650
Appearance
Whitetooff-white

StoringandUsingYourProduct

Storageinstructions
+4°C;
Solubilityoverview
Solubleinethanol(50mM)andDMSO(100mM)
Important
ThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.

ReferencesforAnisomycin

Anisomycinselectivelydesensitizessignallingcomponentsinvolvedinstresskinaseactivationandfosandjuninduction.
Hazzalinetal(1998)MolCellBiol.18(4):1844-54.
PubMedID:9528756
Theproteinsynthesisinhibitoranisomycininducesmacrophageapoptosisinrabbitatheroscleroticplaquesthroughp38mitogen-activatedproteinkinase.
Croonsetal(19286921)JPharmacolExpTher329(3):856-64
PubMedID:19286921
EffectsofanisomycinonLTPinthehippocampalCA1:long-termanalysisusingopticalrecording.
Mochidaetal(2001)Neuroreport12(5):987-91
PubMedID:11303774

品牌介绍

Hello Bio由一群经验丰富的科学家和化学家组成，他们真心希望支持生命科学研究。Hello Bio的目标是生产和供应一系列高质量的生命科学工具，价格如此之低，使尽可能多的研究人员能够买得起。Hello Bio公司的目标是制造和供应一系列高质量的生命科学试剂，产品包括一系列激动剂，拮抗剂，抑制剂，激活剂，抗体和荧光工具，我们公司产品的价格是其他公司产品价格的一半，以便尽可能多的研究人员能够用得起。

公司介绍

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产品分类

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Antagonists & inhibitors Antibiotics Agonists & activators Primary Dyes & stains

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