Product overview

  • NameCMIQ
  • Short descriptionPotent, selective PKA inhibitor
  • Biological descriptionPotent and selective protein kinase A (PKA) inhibitor (IC50 = 30 nM ). Membrane permeable. Blocks ATP-binding site of PKA. Restores morphine-related behaviours in morphine tolerance.
  • Biological actionInhibitor
  • Purity>95%
  • Our products in actionSubmit Your Citation Now


  • Chemical namePKA Inhibitor XI
  • Molecular Weight168.2
  • Chemical structure\"CMIQ
  • Molecular FormulaC11H8N2
  • CAS Number161468-32-2

Storing and Using Your Product

  • Storage instructions+4°C
  • Solubility overviewsoluble in DMSO (50mg/ml)
  • ImportantThis product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for CMIQ

  • PKC and PKA inhibitors reinstate morphine-induced behaviors in morphine tolerant mice.

    Smith FL et al (2006)Pharmacol Res 54(6) : 474-80. PubMedID: 17056270
  • Selective inhibition of cyclic AMP-dependent protein kinase by isoquinoline derivatives.

    Lu ZX et al (1996)Biol Chem Hoppe Seyler 377(6) : 373-84. PubMedID: 8839983
  • Epac mediates a cAMP-to-PKC signaling in inflammatory pain: an isolectin B4(+) neuron-specific mechanism.

    Hucho TB et al (2005)J Neurosci 25(26) : 6119-26. PubMedID: 15987941