Product overview

• NameL-Cysteinesulfinic acid monohydrate
• Short descriptionmGlu_1α / mGlu_5a agonist
• Biological descriptionmGlu_1α and mGlu_5a receptor agonist in RGT cell lines. Also acts as a NMDA receptor agonist and PLD-coupled mGlu receptor agonist.
• Alternative namesL-CSA
• Biological actionAgonist
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Properties

• Molecular Weight171.17
• Chemical structure
• Molecular FormulaC₃H₇NO₄S.H₂O
• CAS Number1115-65-7

Storing and Using Your Product

• Storage instructions-20°C (desiccate)
• Solubility overviewsoluble in water (100mM)
• ImportantThis product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for L-Cysteinesulfinic acid monohydrate

• Sulphur-containing amino acids are agonists for group 1 metabotropic receptors expressed in clonal RGT cell lines.

  Kingston AE et al (1998)Neuropharmacology 37(3) : 277-87. PubMedID: 9681926

• Sulphur-containing excitatory amino acid-stimulated inositol phosphate formation in primary cultures of cerebellar granule cells is mediated predominantly by N-methyl-D-aspartate receptors.

  Gorman A et al (1994)Neuroscience 59(2) : 299-308. PubMedID: 8008194

• L-cysteine sulfinic acid as an endogenous agonist of a novel metabotropic receptor coupled to stimulation of phospholipase D activity.

  Boss V et al (1994)Mol Pharmacol 45(6) : 1177-82. PubMedID: 8022410

• Metabotropic glutamate receptors activate phospholipase D in astrocytes through a protein kinase C-dependent and Rho-independent pathway.

  Servitja JM et al (2003)Neuropharmacology 44(2) : 171-80. PubMedID: 12623215